The Pendleton Oil Mill collapsed on Wednesday, just before 8 p.m.
Pendleton Fire Chief Bobby Pruitt says a mixing tower fell, causing the structure to collapse.
As of 11:30 p.m., East Main is still blocked off by fire trucks on each end.
Pruitt says the mill has been vacant for roughly ten years.
When the building collapsed, much of the debris fell on nearby railroad tracks. Officials say a Norfolk Southern train comes through every night, but has been forced to stop because of the collapse.
The department is still waiting to begin cleanup.
“It’s too unstable. We’re going to have to bring in some big equipment, some tractors in here that can reach up and push it back in on itself. It’s too dangerous to try to get down there and close to it. We got here without anybody being hurt and we’re going to go home without anybody being hurt,” said Pruitt.